Thesis Joyce Pullen

Joyce Pullen

Pharmacokinetics and dosing of antibiotics in neonates

Joyce Pullen

26-4-2007

CONTENTS

Chapter 1: General introduction

Chapter 2: Microanalysis of Amoxicillin, Flucloxacillin, and Rifampicin in neonatal Plasma 

Chapter 3: Population pharmacokinetics and dosing of Amoxicillin in (pre)term neonates

Chapter 4: Amoxicillin Pharmacokinetics in (preterm) infants aged 10 to 52 days: Effect of postnatal age

Chapter 5: Population pharmacokinetics and dosing of Flucloxacillin in preterm and term neonates

Chapter 6: Protein binding of flucloxacillin in neonates

Chapter 7: Pharmacokinetics of intravenous Rifampicin (Rifampin) in neonates

Chapter 8: Application of Artificial neural network modelling of predict Gentamicin clearance in neonates: preliminary study

Chapter 9: General discussion and future perspectives

Summary